Research progress on differentiation of bone marrow stem cell into Schwann cells
10.3760/cma.j.issn.1673-4181.2011.04.009
- VernacularTitle:骨髓间充质干细胞向雪旺细胞诱导分化方法的研究进展
- Author:
Shuang LI
;
Xinlong MA
;
Jianxiong MA
;
Xiaolei SUN
- Publication Type:Journal Article
- Keywords:
Schwann;
Bone marrow mesenchymal stem cells;
Differentiate;
Tissue engineering
- From:
International Journal of Biomedical Engineering
2011;34(4):227-231
- CountryChina
- Language:Chinese
-
Abstract:
Applying cellular transplant methods in the treatment of peripheral nerve injury has become a new hot spot in tissue engineering and drawn much attention. Bone marrow stromal cells (BMSCs) grow fast and can be easily purified in vitro. Besides, they have the capability of differentiating into Schwann cells under specific conditions. For all the reasons above, BMSCs are considered good succedaneum of Schwann cells and new seed cells for tissue engineered peripheral nerve. In this review, the physiological functions and bionomics of Schwann cells and BMSCs are introduced, as well as various methods inducing BMSCs into nerve tissue cells and the foreground of the research.
