Clinical analysis of risk factors of acute kidney injury in patients with chronic kidney disease

VernacularTitle:慢性肾脏病基础上出现急性肾损伤相关因素的临床分析
Author: Li YUAN ; Guihua XU ; Yan LI ; Ping XIE ; Yonghua CHEN ; Jinyuan ZHAO ; Yanling HUANG ; Jie GUO ; Kai CAO
Publication Type:Journal Article
Keywords: Nephrosis; Risk factors; Acute kidney injury
From: Chinese Journal of Postgraduates of Medicine 2011;34(22):16-18
CountryChina
Language:Chinese
Abstract: Objective To evaluate the risk factors of patients with acute kidney injury (AKI) in patients with chronic kidney disease (CKD) for the early detection and early treatment of CKD.Methods One hundred and twenty-seven CKD patients were divided into groups according to AKI existing, 60 cases with out AKI (CKD group), 67 cases with AKI (A/C group) and then A/C group patients were divided into non-older age group (35 cases, ＜60 years old) and older age group (32 cases, ≥60 years old).The protopathy, causative factors and so on were analyzed.Results There was different causative factors in different age group.Logistic regression model indicated that the major risk flactors of AKI in CKD were severe infection (OR = 5.236),hypovolemia (OR = 5.083 ),heart failure (OR = 8.283) and using renal toxicity medicine (OR = 5.246),P ＜ 0.05.Conclusion The major risk factors of AKI in CKD patients include severe infection, hypovolemia, heart failure and renal toxicity medicine.