Clinical significance and change of serum high-sensitivity C-reactive protein in cerebral infarction patients
10.3760/cma.j.issn.1673-4904.2011.22.011
- VernacularTitle:脑梗死患者血清超敏C反应蛋白的改变及其临床意义
- Author:
Jianchuan LI
;
Guomei LI
;
Runhai SUN
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
Brain infarction;
Enzyme -linked immunosorbent assay;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(22):33-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of serum high-sensitivity C-reactive protein (hs-CRP) in cerebral infarction patients and its relationship with the condition of cerebral infarction and prognosis.Methods Ninety-seven cases with cerebral infarction patients (observation group) and 72healthy subjects (control group) were selected.The levels of hs-CRP at different periods were detected by enzyme-linked immunosorbent assay (ELISA) in observation group, and its relationship with the severity of cerebral infarction level degree and neurological deficit scores was analyzed and compared with control group.Results The levels of hs-CRP at the 24th day[(3.9 ± 1.8) mg/L]were lower than those at the 1,4,8th day [(5.8 ± 1.9), (6.4 ± 2.4), (5.7 ± 2.0) mg/L]in observation group, and the difference was significant (P＜ 0.05 ).The levels of hs-CRP showed positive correlation with neurological deficit scores (r = 0.214, P ＜ 0.01 ).Conclusions The levels of hs-CRP have close relationship with cerebral infarction, and it can be used as an important biological indicator in evaluating the severity and prognosis of cerebral infarction and has clinical value in prediction and intervention of cerebral infarction.
