Relationship between osteopontin and hepatocellular carcinoma
10.3760/cma.j.issn.1006-9801.2012.10.024
- VernacularTitle:骨桥蛋白与肝癌关系的研究进展
- Author:
Xiao CHEN
;
Yunjie YE
- Publication Type:Journal Article
- Keywords:
Osteopontin;
Liver neoplasms;
Growth;
Neoplasm metastasis;
Prognosis
- From:
Cancer Research and Clinic
2012;24(10):713-715
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,it has been reported that the osteopontin attracts great attention for its roles in tumor growth and metastasis.In many tumors,osteopontin plays an important role in promoting tumor growth,metastasis and enhancing adhesion and migration abilities.In particular,in hepatocellular carcinoma,osteopontin has very satisfactory sensitivity and specificity in early diagnosis and is relatively effective on prognosis prediction.Suppression osteopontin expression will inhibit liver cancer growth and metastasis,indicating that the osteopontin stays a new target for liver cancer treatment and possesses intangible clinical potential.
