Research progress on YKL-40 protein in tumor
10.3760/cma.j.issn.1006-9801.2012.10.023
- VernacularTitle:YKL-40蛋白在肿瘤中的研究进展
- Author:
Haitao CHEN
- Publication Type:Journal Article
- Keywords:
Neoplasms;
YKL-40 protein
- From:
Cancer Research and Clinic
2012;24(10):711-712
- CountryChina
- Language:Chinese
-
Abstract:
Tissue expression and blood level of YKL-40 protein are elevated ia patients with tumor.The protein may have a role in cancer cell proliferation,infiltration,metastasis and remodelling of tumor stroma.Elevated YKL-40 levels are highly associated with short survival and poor response to treatment for patients.Thus,YKL-40 may serve as a biomarker in diagnosis of disease,evaluation of severity and assessment of prognosis.It's more likely to be a new target for anti-tumor treatment.
