Key points in the surgical treatment of infective endocarditis : a report of 106 cases
10.3760/cma.j.issn.1001-4497.2012.09.006
- VernacularTitle:感染性心内膜炎外科治疗106例
- Author:
Guohua DONG
;
Hua JING
;
Demin LI
;
Xiaonan HU
;
Zhongdong LI
;
Liguo LUO
;
Yi SHEN
;
Biao XU
;
Jianjun QIAN
;
Changtian WANG
;
Xiaohua ZHANG
;
Xiaofeng CHENG
;
Haiwei WU
- Publication Type:Journal Article
- Keywords:
Endocarditis;
Heart valve prosthesis implantation Cardiac;
Surgical Procedures;
Anti-Bacterial Agents
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2012;28(9):530-532
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the clinical experience in the surgical treatment of infective endocarditis,and to summarize the key points of how to elevate therapeutic effect.Methods From Jan 2001 to Dec 2010,106 patients with infective endocarditis who underwent operative therapy were retrospectively analyzed.All patients underwent cardiac operation in conventional hypothermic cardiopulmonary bypass.Vegetations and suspicious infective focus were thoroughly cleaned.Endocardium was swabbed with normal sodium repeatedly and with high concentration antibiotic solution.Combined anomalies were rectified and the affected valves were replaced.Artificial valves were preconditioned with antibiotics before implantation.All patients were treated with full dose of sensitive antibiotics for 6-8 weeks after operation.Results Two patients(1.8％) died perioperatively,1 died of severe pulmonary infection 5 days post operation,and 1 died of multisystem organ failure.Other 104 patients recovered smoothly,95 of whom were followed up for 6 months to 10 years.One patient died,and the other patients recovered with Ⅰ-Ⅱ grade heart function(NYHA).Three patients had anticoagulation related complications.There was no relapse of endocarditis occurred during the period of follow-up.Conclusion Early diagnosis and timely operation on infective endocarditis can achieve satisfactory effect.The thorough sterilization,prosthetic valves precondition and post operative regular antibiotics therapy were the key points of successful surgical treatment.
