Prognosis and staging of non small ceil lung cancer that extends across the fissure into adjacent Iobe
10.3760/cma.j.issn.1001-4497.2011.11.014
- VernacularTitle:跨肺裂型非小细胞肺癌患者手术预后分析及分期探讨
- Author:
Zhengzheng NI
;
Gening JIANG
;
Jiaan DING
;
Wenxin HE
;
Ming LIU
;
Nan SONG
;
Jie YANG
;
Siming JIANG
;
Xiaoxiong XU
- Publication Type:Journal Article
- Keywords:
Cacinoma,non-small-cell lung;
Phneumonectomy;
Neoplasm staging;
Prognosis
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2011;27(11):674-677
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the prognosis and staging non small cell lung cancer (NSCLC) that extends across the fissure into adjacent lobe after surgery.Methods 3752 patients with histopathologically confirmed non small cell lung cancer (NSCLC) received surgical reeessetion from January,1997 to April,2007.Among them,163 patients have a tumor invasion beyond fissure.After matching by pathologic TNM staging (7th),326 patients whose tumor defined in a single lobe were eligible for analysis.Results Histopatholngic staging of matched patients was I a:10 patiens(6.1％ ),I b:79 patients (48.5％),Ⅱa:5 patients (3.1％ ),111:44 patients (27.0％) and Ⅲa:25 patients( 15.3％ ).5 years survival in patients with stage 1 tumors crossing the interlobar fissure was 51％,while in patients not cross the interlobar fissure was 63％ ( P ＜0.05 ).There was no difference in survival for tumors stage Ⅱa and above with regard to importance of interlobar extension.The T2 tumor extending across a lung fissure had a reduction in survival compared with T2 tumor not cross the lung fissure and similar to the T3 tumor without the fissure invasion.Conclusion Our results suggest that TNM staging should be modified for tumor extends the fissure into adjacent lobe.
