Endoscopic ultrasound-guided fine needle aspiration with different needle types for solid pancreatic masses: a prospective and randomized comparative trial in two centers
10.3760/cma.j.issn.1007-5232.2012.07.002
- VernacularTitle:超声内镜引导不同型号细针穿刺胰腺占位病灶的前瞻随机对照研究
- Author:
Liang ZHONG
;
Qi ZHU
;
Tingting GONG
;
Chen JIN
;
Sijie HAO
;
Tingjun YE
;
Yunwei SUN
;
Jihong TAN
;
Lu XIA
;
Dongxin ZHAO
- Publication Type:Journal Article
- Keywords:
Endoscopic ultrasonography;
Biopsy,needle;
Pancreas
- From:
Chinese Journal of Digestive Endoscopy
2012;29(7):364-369
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the diagnostic yield of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for solid pancreatic masses performed with three different needle types through the cytological results.Methods All patients with solid pancreatic masses larger than 2cm from December 2010 to May 2011 were enrolled,and divided into two groups according to different access of EUS-FNA,trans-gastric approach with 19-,22-and 25-gauge needles (n =42) and trans-duodenal approach with 22-and 25-gauge needles (n =10).In both groups,EUS-FNA was performed with randomization of needle types.During the puncture,the suction,the number of movements,and the depth of insertion were fixed.At the end of the puncture,a liquid-based cytological (LBC) preparation was used to fix the specimen.One cytopathologists was assigned to make the diagnosis and comparison.Results Technical success was 100％ and no procedure related complications occurred.No statistically significant differences were observed in different needles in terms of all cytological parameters between two groups (P ＞ 0.05).However,the 25-gauge needle showed a trend towards a higher sensitivity,specificity,positive predictive value,negative predictive value and accuracy.Conclusion There is no significant difference in yield of cytological results between different needle types,although 25-gauge needle shows a relative superiority.
