Digital chrome endoscopy and confocai laser endomicroscopy in diagnosis of Barrett esophagus
10.3760/cma.j.issn.1007-5232.2011.12.011
- VernacularTitle:数字染色内镜及共聚焦激光显微内镜在Barrett食管诊断中的价值研究
- Author:
Peiqi LONG
;
Hui YUE
;
Weifei WANG
;
Qingzhu WEI
;
Zhengguo MAO
;
Sanhua DENG
;
Qianqian PENG
- Publication Type:Journal Article
- Keywords:
Barrett esophagus;
Diagnosis;
I-Scan;
Confocal laser endomicroscopy
- From:
Chinese Journal of Digestive Endoscopy
2011;28(12):688-691
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate digital chrome endoscopy (I-Scan) and confocal laser endomicroscopy (CLE) for diagnosis of Barrett esophagus (BE).MethodsFrom July 2010 to July 2011,a total of 878 outpatients who had upper gastrointestinal symptoms underwent routine endoscopy and I-Scan examination,screened patients with suspected Barrett's epithelial were further referred to CLE and endoscopy.The detection rate and image features of BE between routine endoscopy and I-Scan,and the diagnosis of BE between pathology and CLE,were compared respectively.ResultsSuspected BE was diagnosed in 46 patients (5.2％) by routine endoscopy,and in52 (5.9％) by I-Scan,and there was no significant difference in detection rate between 2 methods (x2 =0.533,P ＞ 0.05 ).The detection rate of paliform blood vessels between SCJ and GEJ was higher using I-Scan (35/52,67.3％ ) than routine endoscope (21/46,45.7％,P ＜0.05).A total of 19 suspected BE underwent CLE and biopsy,and BE was diagnosed by CLE with a sensitivity of 93％ and a specificity of 100％.ConclusionI-Scan is capable of identifying paliform blood vessels between SCJ and GEJ,and can improve the detection rate of suspected BE.CLE is able to provide in-vivo histological diagnosis of BE with a high sensitivity and specificity.
