Cerebralmicrobleeds on magnetic resonance imaging associated with antiplatelet-related intracranial hemorrhage
10.3760/cma.j.issn.1006-7876.2011.10.009
- VernacularTitle:磁共振成像脑微出血与抗栓治疗脑出血相关
- Author:
Zhimin WANG
;
Lei WANG
- Publication Type:Journal Article
- Keywords:
Cerebral hemorrhage;
Thrombolytic therapy;
Magnetic resonance imaging
- From:
Chinese Journal of Neurology
2011;44(10):677-680
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate whether brain microbleeds is associated with antiplatelet-related intracranial hemorrhage (ICH). MethodsForty-three patients with antiplatelet-related ICH treated in our hospital from Jun 2005 to Jun 2010 were investigated in this study.Age, sex and hypertension matched controls with non-antiplatelet-related ICH; and without history of ICH on antiplatelet therapy were selected. ResultsMicrobleeds was more frequent in antiplatelet users with ICH than in matched antiplatelet users without ICH(31/43(72. 1％ ) vs 12/57(21.1％ ), x2 =6. 731, P =0. 011 ) and was more frequent in IHC patients with antiplatelet treatment than those with non-antiplatelet treatment (31/43 (72. 1％ ) vs 17/48 (35.4％), P =0. 030). The frequency of lobar microbleeds(27/43, 62. 8％ ) was significant high in antiplatelet-related ICH than that in non antiplatelet-related ICH (19/48, 39. 6％, x2 =4. 019, P =0. 042). The number of microbleeds was associated with the risk of antiplate-related ICH ( OR =1.38 per additional microbleed, 95％ CI 1.07-1.71, t =0. 806, P =0. 021 ). ConclusionBrain microbleeds are associated with antiplatelet-related ICH.
