Analysis of contact allergens in 1065 patients with dermatitis or eczema in Wuxi city
10.3760/cma.j.issn.0412-4030.2012.10.021
- VernacularTitle:无锡市1065例皮炎湿疹类皮肤病的接触性变应原分析
- Author:
Yan HU
;
Xunyi DAI
;
Lei CAO
;
Xuefen LU
;
Juan ZHANG
;
Ying FAN
;
Aifen ZHOU
;
Lijia YANG
- Publication Type:Journal Article
- From:
Chinese Journal of Dermatology
2012;45(10):747-749
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine contact allergens and their clinical significance in patients with dermatitis or eczema in Wuxi city.MethodsPatch test was conducted in 1065 patients with a clinical diagnosis of dermatitis or eczema.A statistical analysis was carried out.Results Positive patch test reactions were observed in 83.19％ of the patients,with no statistical differences in the frequency of positive patch test reactions between female and male patients or between patients of different age groups.The most frequent 6 allergens were potassium dichromate,cobalt chloride,nickle sulfate,formaldehyde,carba mix and fragrance mix in these patients.Female patients showed a higher frequency of positive patch test reaction to nickle sulfate and formaldehyde,but a lower frequency to potassium dichromate and carba mix compared with male patients (all P＜ 0.01 ); young,middle-aged,and old patients exhibited an increased frequency of positive reaction to cobaly chloride compared with child patients,while young and middle-aged patients showed a decreased frequency to nickel sulfate compared with child patients (all P ＜ 0.05).Conclusion Potassium dichromate,cobalt chloride,nickle sulfate,formaldehyde,carba mix and fragrance mix are the main allergens causing dermatitis and eczema in Wuxi city.
