Clinical and pathological analysis of six cases of eruptive microvenular hemangioma

VernacularTitle:发疹性微静脉血管瘤六例分析
Author: Xiulian XU ; Xuesi ZENG ; Hao CHEN ; Yuanhua CAO ; Suying FENG ; Jianfang SUN
Publication Type:Journal Article
Keywords: Eruptive microvenular hemangioma; Skin manifestations; Pathologic processes
From: Chinese Journal of Dermatology 2012;45(10):697-699
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical and histopathologic features of eruptive microvenular hemangioma (EMVH). MethodsThe clinical and histological findings in six patients with EMVH were retrospectively reviewed.Results The patients were young or middle-aged,with a median age of onset of 34 years.The ratio of males to females was 1 ∶ 1.Clinically,all the patients experienced a sudden development of widespread,asymptomatic,brunneus,flat-topped papules and plaques measuring from 0.1 to 2.0 cm in diameter.Histopathologic examination revealed a poorly circumscribed proliferation of small,irregularly branched,thin-walled blood vessels haphazardly arranged between collagen fiber bundles in the dermis.The lumina of the blood vessels were often collapsed.There was no cellular atypia or mitosis.A variable degree of sclerosis was noted in the surrounding stroma.Immunobistochemical study revealed that the endothelial cells stained positive for CD34,CD31,and factor Ⅷ-related antigen.Conclusions The diagnosis of EMVH is proposed,and awareness of this disease may benefit its early diagnosis and avoidance of unnecessary treatment.