Evaluation of clinical efficacy of three different placental preparations in the treatment of childhood vitiligo

VernacularTitle:三种胎盘制剂联合红外线照射治疗儿童白癜风的临床疗效观察
Author: Tao WANG ; Aie XU ; Xiaodong WEI ; Dong DONG
Publication Type:Journal Article
From: Chinese Journal of Dermatology 2011;44(11):815-817
CountryChina
Language:Chinese
Abstract: ObjectiveTo evaluate the clinical efficacy of three different placental preparations in the treatment of childhood vitiligo.MethodsEighty-two children with vitiligo were divided into 3 groups to be topically treated with melagenine,human placental tissue fluid and human placental lipopolysaccharide respectively.All the patients were additionally treated with infrared rays for 20 minutes twice daily.The drugs were topically applied with an interval of 5 minutes during the irradiation.ResultsThe response rate was 75.65％,35.00％ and 44.44％ respectively in the melagenine-,human placental tissue fluid- and human placental lipopolysaccharide-treated patients,and significant differences were observed between the three groups of patients(all P ＜ 0.05).In particular,melagenine was superior to the other two preparations for the treatment of large areas of vitiligo on the scalp.ConclusionThe 3 placental preparations combined with infrared irradiation show favorable efficacy for the treatment of childhood vitiligo.