Toxic megacolon complicated by ulcerative colitis in six patients:a case report and literature review

VernacularTitle:溃疡性结肠炎合并中毒性巨结肠六例及文献复习
Author: Weiyang ZHENG ; Jiaming QIAN ; Huaxia YANG ; Feng ZHU ; Jingnan LI
Publication Type:Journal Article
Keywords: Colitis,ulcerative; Megacolon,toxic; Diagnosis; Therapy
From: Chinese Journal of Internal Medicine 2012;51(9):694-697
CountryChina
Language:Chinese
Abstract: ObjectiveTo summarize the clinical features of ulcerative eolitis (UC) complicated by toxic megacolon for early diagnosis and proper treatment. MethodsSix cases of toxic megacolon in the patients suffered from UC in Peking Union Medical College Hospital from 1983 to 2010 were analyzed,and related literature was searched and reviewed.ResultsThe incidence of the toxic megacolon in the patients with UC in our center was 0.7％ (6/824),which was lower than those reported in the literature.There were always risk factors triggering the disease.The prognosis of the patients was poor,even after medical care and surgery intervention.Evaluation of the patients and making right timing to perform the surgery would improve the prognosis of the patients in foreign literature. ConclusionIt's crucial to make early diagnosis of the toxic megacolon in the patients suffered from UC. The right choice and timing to perform urgent surgery or selective surgery may improve their prognosis.