The evolving field of tyrosine kinase inhibitors in the treatment of thyroid carcinoma
10.3760/cma.j.issn.1000-6699.2012.10.003
- VernacularTitle:靶向药物酪氨酸激酶抑制剂治疗甲状腺癌的临床研究进展
- Author:
Haixia GUAN
;
Lei YE
- Publication Type:Journal Article
- Keywords:
Thyroid carcinoma;
Targeted therapy;
Tyrosine kinase inhibitors
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(10):798-801
- CountryChina
- Language:Chinese
-
Abstract:
The outstanding progress in the molecular basis of thyroid carcinoma has offered a tool for the development of new drugs,mainly tyrosine kinase inhibitors (TKIs).A number of TKIs are now being applied to the treatment of thyroid carcinomas.Recent clinical trials of TKIs in patients with advanced thyroid cancer have shown some promising preliminary results.This review summarizes the most relevant achievements in the field and the challenges we are facing.