Prognosis comparison of bladder neck with seminal vesicle invasion after radical operation of prostate carcinoma
10.3760/cma.j.issn.0254-9026.2012.11.004
- VernacularTitle:前列腺癌根治术后膀胱颈部与精囊侵犯的预后比较
- Author:
Jianjun SHA
;
Xiaorong WU
;
Jiahua PAN
;
Lianhua ZHANG
;
Hanqing XUAN
;
Dong LI
;
Wei XUE
;
Juanjie BO
;
Dongming LIU
;
Yiran HUANG
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Neoplasm metastasis;
Prognosis
- From:
Chinese Journal of Geriatrics
2012;31(11):938-940
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the prognosis of patients with bladder neck (BN) involvement in radical prostatectomy specimens and compare it with patients with seminal vesicle invasion (SVI).Methods From January 2002 to December 2008,42 patients with prostate carcinoma who underwent radical prostatectomy were analyzed retrospectively.The mean age was 70.3 years (range 59-78 years).The patients were divided into two groups according to 2002 TNM system:pT4a group (bladder neck invasion) with 17 cases and pT3b group (unilateral or bilateral seminal vesicle invasion)with 25 cases.Postoperative outpatients were followed-up on a regular basis,two consecutive postoperative serums PSA greater than 0.2 μg/L defined as a biochemical recurrence.The postoperative follow-up to the time of biochemical recurrence or follow up to the deadline without biochemical recurrence were defined as biochemical recurrence free survival time.Results All patients were followed up for 50-122 months.The patients with BN involvement 17.6％ (3/17) had biochemical recurrence,whereas seminal vesicle invasion 24.0％ (6/25),there was no statistical significance between the two groups (P＞0.05).Conclusions Postoperative adjuvant therapies can improve the biochemical recurrence free survival.In this study,the prognosis of pT4a and pT3b group is similar.A conceivable down-staging of BN involvement in the TNM staging system should be considered.
