Curative effect of insulin glargine plus acarbose in the treatment of elderly type 2 diabetes complicated with cerebral infarction
10.3760/cma.j.issn.0254-9026.2012.10.016
- VernacularTitle:甘精胰岛素联合阿卡波糖治疗老年糖尿病合并脑梗死患者的临床疗效分析
- Author:
Hailin SHAO
;
Jiyuan FAN
;
Chunqing SONG
;
Donghong XIU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type2;
Brain infarction;
Insulin,long-acting;
Acarbose
- From:
Chinese Journal of Geriatrics
2012;31(10):885-886
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the curative effect of insulin glargine plus acarbose in the treatment of elderly type 2 diabetes and cerebral infarction.Methods Totally 84 elderly patients with type 2 diabetes and cerebral infarction were received insulin glargine and acarbose for 16 weeks.The levels of fasting plasma glucose (FPG),hemoglobin A1c (HbA1c),Postprandial glucose values of 2 h (2 hPG),Postprandial C peptide (PCP) and Fasting C peptide (FCP) before and after treatment were detected.Results Compared with pretreatment,the levels of FPG,HbA1c and 2 hPG after treatment were decreased to (6.87 1.46) mmol/L (t =1.658,P＜0.05),(6.48±1.12)％ (t=1.629,P＜0.05) and (8.34±2.15) mmol/L (t=2.037,P＜0.05),respectively,while PCP and FCP were increased to (3.82±0.22) μg/L and (3.52±0.36) μg/L (t=2.698,t=2.087,bothP＜0.05).Conclusions Combined insulin glargine with acarbose in the treatment of elderly type 2 diabetes and cerebral infarction can effectively reduce fasting and postprandial blood glucose,and improve the function of islet β cells.
