Application of dual-source CT in the evaluation of hepatocellular carcinoma after transarterial chemoembolization treatment
10.3760/cma.j.issn.1005-1201.2011.10.020
- VernacularTitle:双源CT双能量成像在肝癌经皮肝动脉化疗栓塞术后复查中的应用价值
- Author:
Ruimei CHAI
;
Ke REN
;
Sheng QU
;
Qiang FU
;
Qiang WANG
;
Wenheng ZHENG
;
Ke XU
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Radiology,interventional;
Tomography,X-ray computed
- From:
Chinese Journal of Radiology
2011;45(10):980-984
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo assess the diagnostic value of dual-energy dual-source CT in detecting the enhancement ofhepatocellularcancer( HCC )aftertransarterialchemoembolization( TACE )treatment.Methods Twenty-seven patients with HCC underwent dual-energy dual-source CT including nonenhanced,arterial,portal,and delayed phases scanning after TACE treatment.Arterial phases were acquired with the dual-energy mode for reconstruction of virtual nonenhanced images and color overlay images.DSAs were performed in all these patients.Two blinded and independent readers evaluated the data in 2 reading sessions:standard nonenhanced,arterial phase,portal phase,and delayed phase images were read in session A,and virtual nonenhanced,arterial phase,portal phase,and delayed phase images in session B.Sensitivity and specificity were calculated,with the DSA data set as the reference standard.The sensitivity and specificity were compared with Chi-square test.Results DSA revealed 63 lesions in 27 patients,and 39 of them had blood supply.Overall sensitivity and specificity were 74.4％ (29/39) and 83.3％ (20/24) for session A,and 94.9％ (37/39),95.8％ (23/24) for session B,respectively.The sensitivity of the two reading sessions was significantly different (x2 =6.303,P ＜ 0.05 ),while the specificity was insignificantly different ( x2 =2.009,P ＞ 0.05 ).Conclusion Compared with standard dynamic protocols,an arterial dual-energy dual-source CT scan with reconstruction of virtual nonenhanced and color overlay images enables detection of relapse and intrahepatic metastasis of HCC after TACE treatment with higher accuracy.
