Epidemiologic study of children admitted to hospital with Kawasaki disease in Wenzhou from 2001 to 2010
10.3760/cma.j.issn.1007-7480.2012.11.011
- VernacularTitle:2001-2010年温州地区川崎病住院患儿流行病学调查
- Author:
Yingying ZHANG
;
Yuanhai ZHANG
;
Aihua ZHOU
;
Dan WANG
;
Yayan YUE
;
Lulu PAN
;
Rongzhou WU
;
Qi CHEN
;
Rulian XIANG
;
Maoping CHU
- Publication Type:Journal Article
- Keywords:
Mucocutaneous lymph node syndrome;
Epidemiology;
Child
- From:
Chinese Journal of Rheumatology
2012;16(11):763-766
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evalute the incidence and epidemiologic characteristics of Kawasaki disease (KD) in Wenzhou,China.Methods We used a questionnaire survey and reviewed the medical records and reports of all patients with KD diagnosed during the 10 year periods from January,2001 to December,2010.Results We studied 827 inpatients diagnosed with KD during the 10-years period from 2001 to 2010.There were 613 cases (74.12％) with complete KD.The ratio of male to female ratio was 2.28∶1.Age at onset ranged from 37 days to 13 years old,and the peak age group was 1 year old.The disease occurred in all of the seasons,but the peak was from April to June.The incidence of cardiovascular damage in acute KD was 34.6％,and the most common sequela was coronary artery dilatation.There were16 patients with coronary aneurysm.Fifty-three patients did not respond to immunoglobulin (6.4％),and 12 patients (1.5％) developed recurrent KD.After treatment,114 cases (13.8％) developed neutropenia.There were no deaths during hospitalization.Conclusion Patients with KD has become more and more in Wenzhou.Cardiovascular damages were similar to those in Beijing and Guangzhou,but higher than that reported in Japan.
