The lung CT findings in patients with primary Sj(o)gren's syndrome and clinical significance
10.3760/cma.j.issn.1007-7480.2012.11.002
- VernacularTitle:原发性干燥综合征肺部CT表现及临床意义
- Author:
Yilei CHEN
;
Minguang ZHANG
;
Jun WANG
;
Yingjiang ZHAN
;
Jianchu CHEN
- Publication Type:Journal Article
- Keywords:
Sj(o)gren's syndrome;
Tomography,X-ray computed;
Pulmonary arterial hypertension;
SSB antibodies
- From:
Chinese Journal of Rheumatology
2012;16(11):724-727
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the lung CT findings in patients with primary Sj(o)gren's syndrome (pSS) and clinical significance.Methods Images of lung CT scans of 68 patients with pSS were retrospectively observed.The distribution characteristics of lung lesions were observed.CT visual score were used to quantitatively analyze lung lesions.Binary classification unconditional logistic regression analysis was used to investigate the relationship between pulmonary arterial hypertension (PAH) and anti-SSB seropositivity in Patients with pSS.Results The 68 cases of patients with pSS,PAH in 13 (19％),anti-SSB seropositivity in 25(37％),CT shows normal in 13 (19％),interlobular septal thickening,ground-glass opacity and intralobular interstitial thickening were frequent findings.The lesion distribution was in the peripheral and lower lung fields.Interlobular septal thickening and cysts were associated with PAH in Patients with pSS (OR=1.780,2.513,P＜0.05),cysts was significantly associated with anti-SSB seropositivity (OR =10.530,P＜0.05).Conclusion Lung CT can quantitatively analyze the degree of pSS lung damage,and provide helps for clinical treatment and prognosis.
