Predictive value of intraperitoneal drainage fluid sTREM-1 in sepsis secondary to abdominal trauma
10.3760/cma.j.issn.1001-8050.2012.09.016
- VernacularTitle:腹腔引流液sTREM-1对腹部创伤后并发脓毒症的预测价值
- Author:
Yaosheng MAO
;
Miaoying CAO
;
Tie Lü
;
Zhixin LI
;
Xin ZHOU
- Publication Type:Journal Article
- Keywords:
Abdominal injuries;
Sepsis;
Soluble triggering receptors expressed on myeloid cells-1
- From:
Chinese Journal of Trauma
2012;28(9):818-822
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of soluble triggering receptors expressed on myeloid cells-1 ( sTREM-1 ) in intraperitoneal drainage fluid of patients with abdorminal trauma and its predictive value for post-traumatic sepsis. Methods A total of 80 abdominal trauma patients were served as the trauma group and 25 patients treated with subtotal gastrectomy as the control group.Intraperitoneal drainage fluid sTREM-1,serum sTREM-1,procalcitonin (PCT) and C-reactive protein (CRP)at 0,24,48,72 hours after admission were determined in two groups for assessing their value in early prediction of post-traumatic sepsis. Results The levels of drainage fluid sTREM-1,serum sTREM-1,PCT and CRP in the trauma group were significantly higher than those in the control group (P ＜ 0.05 ).Drainage fluid sTREM-1 showed the area under the receiver operating characteristic (ROC) curve,sensitivity and specificity for 0.84,77％,and 83％ in the prediction of post-traumatic sepsis,which was superior to the serum sTREM-1,PCT and CRP. Conclusion Intraperitoneal drainage fluid sTREM-1 has high accuracy in predicting the sepsis in abdominal trauma patients.
