Analysis of functional splenic artery blood flow embolization in the treatment of hypersplenism
10.3760/cma.j.issn.1008-6315.2012.12.030
- VernacularTitle:功能性脾动脉血流栓塞治疗脾功能亢进的近期效果观察
- Author:
Junhua ZHANG
;
Jinlong ZHANG
;
Xiao YANG
;
Hui WANG
;
Rui LIU
;
Yu LI
- Publication Type:Journal Article
- Keywords:
Partial splenic embolization;
Hypersplenism;
Leukocyte
- From:
Clinical Medicine of China
2012;28(12):1328-1330
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively analyze the efficacy and safety of splenic embolization in the treatment of hypersplenism.Methods Thirty-six cases of hepatocellular carcinoma patients with cirrhosis,splenomegaly and hypersplenism underwent hepatocellular carcinoma embolization as well as with spleen embolization.White blood cells (WBC) and platelets were tested and postoperative clinical reactions were observed at 3,7,30 days and 3-6 months after the operation.Results The number of WBC and platelet were both significantly increased after the operation,the difference was significantly statistical [WBC:3 d:( 9.4 ±2.1 ) × 109/L,7 d:(9.3 ± 2.3 ) × 109/L,30 d:( 8.6 ± 2.1 ) × 109/L,3 months:( 6.4 ± 1.6 ) × 109/L vs (2.6 ± 1.4) × 109/L,P＜0.01;platelet:3 d:(94 ±23) × 109/L,7 d:(140 ±32) × 109/L,30 d:(136 ±38) ×109/L,3 months:( 119 ±26) × 109/L vs (32 ± 18) × 109/L,P＜0.01].All patients got fever,loss of appetite,nausea and pain in the spleen,of which 6 patients needed clinical treatment to control symptoms and left pleural effusion occurred in 3 patients,but without cases with serious complications.Conclusion The functional splenic artery blood flow embolization is a safe and effective treatment for liver cirrhosis caused by hypersplenism.
