Surveillance of pathogens from patients with hospital infection and analysis of drug resistance in intensive care unit

VernacularTitle:重症监护病房医院感染病原菌监测及耐药性分析
Author: Yuhong LIU ; Jianfeng ZOU ; Xiuhong HAO ; Yuekun ZOU ; Zhicheng ZHANG
Publication Type:Journal Article
Keywords: Intensive care unit; Nosocomial infection; Surveillance of pathogens; Drug resistance
From: Clinical Medicine of China 2012;28(12):1293-1295
CountryChina
Language:Chinese
Abstract: Objective To review the prevalence of nosocomial infection and the change of drug resistance in a comprehensive intensive care unit (ICU) and to provide theoretical basis for clinical prevention and treatment.Methods The strains of bacteria and fungi were isolated from ICU and their drug resistance was retrospectively analyzed from Jan.1st,2010 to Dec.31th,2011.Results The main pathogen of nosocomial infection were Gram-negative bacteria ( 73.3％ ),Gram-positive bacteria ( 17.9％ ) and fungi ( 8.7％ ).In bacterial infection,Gram-negative and G-positive bacteria accounted for 80.3％ and 19.7％ respectively.In Gram-negative bacteria,pseudomonas aeruginosa was the major type (21.7％).In Gram-positive bacteria,staphylococcus aureus (31.4％) was most prominent.Drug resistance of bacteria was severe,while that of fungi was mild.Conclusion Bacteria has severe drug resistance and exhibits multi-drug resistance for commonly used antibiotics.The principle of antibiotics application should be mastered and antibiotics should be chosen according to drug-sensitivity tests.