Clinical features of immunocompetent patients with Penicilliosis marneffei
10.3760/cma.j.issn.1008-6706.2012.21.001
- VernacularTitle:免疫功能正常的马尔尼菲青霉病临床特征
- Author:
Wuming LI
;
Zhihao MENG
;
Xiuwen TANG
;
Cunxu LIU
;
Jingjie CHEN
- Publication Type:Journal Article
- Keywords:
Penicillium marneffei;
Infect;
Treatment outcome
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(21):3201-3202
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical features of immunocompetent patients with Penicilliosis marneffei.Methods To analyze and summarize the clinical data of 4 immunocompetent patients with Penicilliosis marneffei.Results Clinical manifestation of patients centered on intermittent slight or mild fever,lymphadenectasis,skin eruptions,osteolytic destruction,anaemia,and leukocytosis.The cultural Penicillium marneffei in specimen such as blood,pus showed a higher positive rate.Amphotericin B and itraconazole was available in treatment.Conclusion Immunocompetent people can be infected by Penicillium marneffei,and they appear nonspecific in clinical manifestation after infection.A timely and effective antifungal therapy can improve the prognosis of patients.
