Antibiotic prophylaxis for transrectal prostate biopsy:the value of rectal swab culture and targeted antimicrobial treatment
10.3760/cma.j.issn.1673-4203.2012.10.008
- VernacularTitle:定向抗菌预防法在防治经直肠前列腺穿刺活检术后感染中的应用价值
- Author:
Jiuzhi LI
;
Xueyi WANG
;
Bin WEN
;
Chao SONG
- Publication Type:Journal Article
- Keywords:
Antibiotic prophylaxis;
Prostate;
Biopsy;
Bacteria culture;
Antimicrobial sensitivity test
- From:
International Journal of Surgery
2012;39(10):668-671
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the targeted antimicrobial prophylaxis in men undergoing trans-rectal ultrasound guided prostate biopsy based on rectal swab culture results.Methods From July 2008 to April 2012 we studied differences in infectious complications in men who received targeted vs standard empirical ciprofloxacin prophylaxis before transrectal ultrasound guided prostate biopsy.All 344 patients were divided into 3 groups according to their hospital records,inculding group A:without antimicrobial prophylaxis(105 eases) ;group B:antimicrobial prophylaxis with fluoroquinolone(117 cases) ;group C:targeted prophylaxis used rectal swab cultures results(122eases).All cases received enema with diluted iodophors before biopsy.We identified men with infectious complications within 7 days after transrectal ultrasound guided prostate biopsy using the electronic medical record,following 3 conditions.Results In group A of 105 case,17 cases of fever were recorded,including prostatic abscess of 3 cases and septicemia of 1 case.Three cases of fever were occurred in group B,including 1 case of bacteremia and 1 case of prostatitis.No infectious complications were recorded in group C.Conclusions Targeted antimicrobial prophylaxis was associated with a notable decrease in the incidence of infections complications after transrectal ultrasound guided prostate biopsy,although fiuoroquinolone can provide good protective effets.
