Normal apparent diffusion coefficient values of different regions of pancreas
10.3760/cma.j.issn.1674-1935.2012.05.006
- VernacularTitle:胰腺不同部位表观扩散系数正常值初探
- Author:
Chunshu PAN
;
Chao MA
;
Jian WANG
;
He WANG
;
Shiyue CHEN
;
Huagao ZHANG
;
Jianping LU
- Publication Type:Journal Article
- Keywords:
Pancreas;
Diffusion magnetic resonance imaging;
Apparent diffusion coefficient
- From:
Chinese Journal of Pancreatology
2012;12(5):310-312
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate and determine the apparent diffusion coefficient (ADC) values in different anatomical regions of normal pancreas.Methods A total of 383 volunteers with normal pancreas were included in this study.Single-shot echo planar imaging diffusion weighted imaging (SSEP-DWI; b value =0,500 s/mm2) was employed to determine the ADCs in the head,neck,body and tail parts of the pancreas.Statistical analysis was performed by using Kruskal-Wallis and Wilcoxon signed rank tests.Results The ADCs in the head,neck,body and tail parts of the pancreas was (1.52 ± 0.29) × 10-3,( 1.64 ± 0.34) ×10-3,(1.67±0.35) × 10-3,(1.58 ±0.31) × 10-3 mm2/s,the Kruskal-Wallis test results showed a significant difference of mean ADCs among the different anatomical regions (chi square =44.8748,P <0.0001 ).Wilcoxon signed rank test results showed the mean ADCs differed remarkably between the head and neck ( P < 0.0001 ),head and body ( P < 0.0001 ),head and tail ( P =0.0008 ),neck and tail (P =0.0062 ),body and tail (P <0.0001),respectively.The mean ADCs between the neck and body was not significantly different (P =0.1181 ).Conclusions The mean ADC values of normal pancreas vary significantly within different anatomical regions,which can serve as a guide for DW1 and ADC in clinical application and research of pancreatic diseases.