The influence of mini-invasive evacuation of hematoma for myelin basic protein and neuronspecific enolase in patients with cerebral hemorrhage
10.3760/cma.j.issn.1673-4904.2012.29.009
- VernacularTitle:脑出血患者微创血肿清除术对髓鞘碱性蛋白及神经元特异性烯醇化酶变化的影响
- Author:
Fanjun MENG
- Publication Type:Journal Article
- Keywords:
Surgical procedures,minimally invasive;
Cerebral hemorrhage;
Myelin basic proteins;
Phosphopyruvate hydratase
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(29):22-25
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the influence of mini-invasive evacuation of hematoma for myelin basic protein (MBP) and neuron-specific enolase (NSE) in patients with cerebral hemorrhage.Methods Eighty patients with cerebral hemorrhage were divided into group A and group B by random digits table method with 40 cases each.The patients in group A were given conservation treatment.The patients in group B were given mini-invasive evacuation of hematoma treatment.At the same time 30 cases of healthy people randomly were selected as control group.The serum MBP and NSE were determined before treatment,after treatment 1,3,7,14 d in group A and group B.ResultsThe effective rate in group B was 92.5％ (37/40),which was higher than that in group A [80.0％(32/40)],there was significant difference (P ＜ 0.05 ).The serum NSE before treatment in group A and group B was higher than that in control group [ (12.8 ± 2.9),( 13.1 ± 2.8 ) μg/L vs.( 5.3 ± 2.4) μg/L],there was significant difference(P ＜ 0.05 ).The serum NSE after treatment in group B was obviously decreased compared with group A.The serum MBP after treatment 1 d was increased,7 d was decreased,that in group B was obviously decreased compared with group A [ (5.4 ± 1.5) μ g/L vs. (6.9 ± 1.3) μ g/L,P ＜ 0.05 ].ConclusionThe method of mini-invasive evacuation of hematoma in treatment of cerebral hemorrhage patients has good effect,and can decrease the serum MBP and NSE.
