Mechanism and significance of immunological changes in sepsis
10.3760/cma.j.issn.1673-4912.2012.05.005
- VernacularTitle:脓毒症时机体免疫机制变化及意义
- Author:
Jianping TAO
- Publication Type:Journal Article
- Keywords:
Sepsis;
Toll-like receptors;
Neutrophils;
Dendritic cells;
Regulatory T cells;
Th1/Th2
- From:
Chinese Pediatric Emergency Medicine
2012;19(5):462-465
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is thought to be systemic inflammatory response syndrome that is activated by invasive infection and characterized by the involvement of inflammation,infection,immunological reaction,coagulation and tissue damage.The imbalance between the pro-and anti-inflammatory response mediated by immunologic disorder plays an important part in the progress of sepsis.Therefore,the immunological mechanisms and changes of Toll-like receptors,neutrophils,dendritic cells and regulatory T cells in sepsis are briefly focused on in the article.
