Meta- analysis of effects of intermittent subglottic secretion drainage on ventilator- associated pneumonia
10.3760/cma.j.issn.1672-7088.2012.29.085
- VernacularTitle:间歇声门下滞留物吸引对呼吸机相关性肺炎影响的Meta分析
- Author:
Xiaoqin WU
;
Jinping SONG
;
Xia SU
- Publication Type:Journal Article
- Keywords:
Attractable tracheal catheter, Subglottic secretion drainage;
Ventilator- associated pneumonia;
Meta analysis
- From:
Chinese Journal of Practical Nursing
2012;28(29):68-70
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the effects of intermittent subglottic secretion drainage(SSD)with an endotracheal tube on incidience of ventilator- associated pneumonia(VAP). MethodsWe searched computerized databases,including Cochrane library,Pubmed,EMbase,CBM,CNKI,Wanfang and some relevant databases from initializing to March 2012,extracting data about subglottic secretion drainage(SSD)with an endotracheal tube on incidence of VAP using RCT.The data had Meta- analysis by software RevMan5,and to those data which could not be conversed or merged,they underwent descriptive analysis. ResultsWeidentifled 5 randomized clinical trials that met the inclusion criteria with a total of 683 randomized patients.In Meta- analysis,the overall risk ratio for ventilator- associated pneumonia was decreased significantly by intermittent subglottic secretion drainage with an endotracheal tube.There was no significant difference on adverse events or on hospital or intensive care unit mortality.Databases,including ICU and hospital LOS,duration of endotracheal catheterization,bacteria concentration,which were difficult to be conversed and obtained full data,they underwent a descriptive research. ConclusionsCompared with the common endotracheal tubes,the use of endotracheal tubes with subglottic secretion drainage is effective for prevention of ventilatorassociated pneumonia.But it has no effect on adverse events or on hospital or intensive care unit mortality.So large sample RCTs with multiply- center should be carried out to assess the effect of the use of SSD.