"Research of correlation of characteristic symptoms and indexes of ""brain collateral damage"" at acute stage of stroke"
10.3760/cma.j.issn.1673-4246.2012.10.001
- VernacularTitle:中风病急性期“毒损脑络”特征症状与实验室指标相关性研究
- Author:
Jing QU
;
Yihuai ZOU
- Publication Type:Journal Article
- Keywords:
Brain collateral damage;
Characteristic symptoms;
Biological parameter
- From:
International Journal of Traditional Chinese Medicine
2012;34(10):865-869
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the correlation of characteristic symptoms and indexes of brain collateral damageat acute stage of stroke.MethodsSeventy cases who got stroke within 72 hours were included.Five nonspecific symptoms and 6 indexes were observed at two time points.ResultsThere were positive correlations between the number of nonspecific symptoms and the value of Hs-CRP,IL-6,OX-LDL,NSE.The correlation coefficients were 0.307,0.289,0.342,0.253 and P<0.05.Nonspecific symptoms appeared in 1 to 3 groups,altogether 40 cases were involved,and the groups had significant deviation compared with the groupwithoutnonspecificsymptomsonOX-LDL(32.37 ± 31.17)μg/l, NSE(2.82 ± 1.25)ng/ml,MMP-9 (214.97± 137.88) ng/ml and P<0.05.Single symptom especially dull expression and hypersomnia were proved to be related with the indexes.For example,the correlation coefficient was 0.318 between hypersomnia and Hs-CRP.The correlation coefficient was 0.384 between dull expression and IL-6.Conclusion Characteristic symptoms were well correlated and ganged with the indexes from different view or level.It acted as representative combination of brain collateral damage syndrome.