Research on the effect of Dachaihu decoction on plasma inflammatory cytokines of acute pancreatitis patient
10.3760/cma.j.issn.1673-4246.2012.10.007
- VernacularTitle:大柴胡汤灌肠对急性胰腺炎患者血浆炎性因子的影响
- Author:
Yongquan LIN
;
Lihua RONG
- Publication Type:Journal Article
- Keywords:
Dachaihu decoction;
Acute pancreatitis;
Plasma inflammatory cytokines
- From:
International Journal of Traditional Chinese Medicine
2012;34(10):886-887
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe effect of Dachaihu decoction on plasma inflammatory cytokines of acute pancreatitis patients.Methods186 cases of acute pancreatitis were randomly recruited into TCM group and control group.The control group was given routine treatment.On the basis of the control group,the TCM group was given Dachaihu decoction for enema additionally,twice daily,7 days.Then plasma inflammatory cytokines level was tested in both groups.ResultsTCM group had lower levels of TNF-α [ (42.18 ± 20.57) mg/L、(22.06± 10.73) mg/L,(9.88 ±4.62)mg/L],IL-1β[ (0.28 ±0.11) μg/L,(0.19±0.02) μg/L,(0.18 ±0.06)μg/L],and IL-6[(87.90±49.41)ng/L,(16.59±10.24) ng/L,(14.96±11.42) ng/L] at 2/5/7 days than the control group.There were statistical difference (P＜0.05).ConclusionEnema with Dachaihu decoction was effective on reducing plasma inflammatory cytokines level.It was probably the key to cure acute pancreatitis.
