Shengqing-Jiangzhuo decoction with western conventional therapy on blood pressure,lipids and glycated hemoglobin in patients with metabolic syndrome
10.3760/cma.j.issn.1673-4246.2012.10.009
- VernacularTitle:升清降浊汤为主对代谢综合征患者血压、血脂及糖化血红蛋白的疗效观察
- Author:
Yuping WANG
;
Jie GUO
;
Hong LIU
- Publication Type:Journal Article
- Keywords:
Metabolic syndrome;
Shengqing-Jiangzhuo decoction;
Lipids;
Glycosylated hemoglobin;
Body Mass Index
- From:
International Journal of Traditional Chinese Medicine
2012;34(10):890-892
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effects of Shengqing-Jiangzhuo decoction combined with western medicine on metabolic syndrome.Methods120 patients with metabolic syndrome in Gaomi City People's Hospital of Traditional Chinese Medicine from March 2008 to July 2011 were randomly divided into a treatment group and a control group according to case number,with 60 cases in each group.The control group was treated with Western medicine individualized and symptomatic treatment,while on the basis of the control group the treatment group was additionally treated with Shengqing-Jiangzhuo decoction.Both groups were continuously treated for 2 months.The main symptoms of the two groups of patients before and after clinical efficacy as well as blood pressure,body mass index (BMI),waist-hip ratio (WHR) lipid levels,glycosylated hemoglobin (HbA1C) changes were observed.Results① The clinical efficacy:After treatment,dizziness,dry mouth,constipation,bloating,irritability and other symptoms improved significantly,with 85.00％ and 73.33％ of the total effective rate in treatment group and control group respectively; ② laboratory parameters detection:there was statistical difference between the control group and the treatment group in terms of systolic blood pressure (127.30±8.00) mm Hg,diastolic blood pressure (81.35±3.81) mm Hg,body mass index (23.3±1.48),waist-hip ratio (0.85 ± 0.07),as well as cholesterol (3.32 ± 0.81)mmol/L triglyceride (1.76 ±1.01) mmol/L,low-density lipoprotein cholesterol (2.20±0.72)mmol/L,high density lipoprotein cholesterol (1.39±0.14) mmol/L,glycosylated hemoglobin (6.58±0.82) mg/dl,(P＜0.05 or P＜0.01).Conclusion Shengqing-Jiangzhuo decoction significantly improved the clinical efficacy of metabolic syndrome.
