Research progress of laminin-111 in angiogensis
10.3760/cma.j.issn.1673-4203.2012.09.012
- VernacularTitle:层粘连蛋白-111在血管生成中作用的研究进展
- Author:
Jinjin LI
;
Junwei WU
;
Xinqun CHAI
- Publication Type:Journal Article
- Keywords:
Laminin;
Neovascularization,pathologic;
Extmcellular matrix
- From:
International Journal of Surgery
2012;39(9):608-612
- CountryChina
- Language:Chinese
-
Abstract:
Laiminin,which has been found 15 isoforms up to today,is a kind of noncollagen glycoprotein of extracellular matrix.However,the functions of laminin varis from each other,which mainly takes participation in the process of the cell adherence,migration,differentiation,growth,cell signaling and tissue repair in vivo.In recent years,some scholars have found that laminin plays an important role in angiogenesis.The purpose of this article is to summarize the role of laminin in angiogensis and sum up the current research progress.
