Research progress of gallbladder carcinoma and neoplastic stem cells
10.3760/cma.j.issn.1673-4203.2012.09.014
- VernacularTitle:胆囊癌与肿瘤干细胞关系的研究进展
- Author:
Yuanlin YU
;
Bojian JIANG
;
Jiwei YU
- Publication Type:Journal Article
- Keywords:
Gallbladder neoplasms;
Neoplastic stem cells;
CD133;
CD44;
SP cells;
Drug resistance,neoplasms
- From:
International Journal of Surgery
2012;39(9):615-618
- CountryChina
- Language:Chinese
-
Abstract:
Gallbladder carcinoma is the most common malignant tumor in biliary system,the early diagnosis rate is still very low and the prognosis is extremely poor.At present,the pathogenesis of gallbladder is not clear.Recently,with the development of the neoplastic stem cell research on gallbladder carcinoma,the latest study showed SP positive cells could be separated from the GBC-SD cell.Further more,related researches have shown that gallbladder respectively with CD133+ cells,CD44+ cells,CD133+ CD44+ cells had possessed the cloned formation ability,the stronger growth ability,the differentiation capacity and forming-tumor ability.In this review,we will discuss the research of the relationship between the gallbladder carcinoma and neoplastic stem cells.
