Endothelin-1 and cerebral vasospasm after subarachnoid hemorrhage
10.3760/cma.j.issn.1673-4165.2012.08.016
- VernacularTitle:内皮素-1与蛛网膜下腔出血后脑血管痉挛
- Author:
Xiaoming ZHOU
;
Mengliang ZHOU
;
Xin ZHANG
- Publication Type:Journal Article
- Keywords:
Subarachnoid Hemorrhage;
Vasospasm,Intracranial;
Endothelin-1;
Brain Ischemia
- From:
International Journal of Cerebrovascular Diseases
2012;20(8):637-640
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral vasospasm (CVS) is a serious complication of aneurysmal subarachnoid hemorrhage (SAH).Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictor substance.A large number of clinical and basic studies have shown that cerebrospinal fluid and/or ET-1 levels in peripheral blood increases in patients with SAH and play an important role in the occurrence and development of CVS.This article reviews the research status of the role of ET-1 in the occurrence and development of CVS.
