Radioactive stents for advanced extra-hepatic cholangio-carcinoma

VernacularTitle:放射性粒子支架治疗进展期肝外胆管癌的临床研究
Author: Yan GUO ; Yan LIU ; Zheng LU ; Dong WANG ; Duowu ZOU ; Feng LIU ; Zhendong JIN ; Shude LI ; Xianbao ZHAN ; Zhaoshen LI
Publication Type:Journal Article
Keywords: Cancer of bile duct; Brachytherapy; Stent; Iodine radioisotopes
From: Chinese Journal of Digestive Endoscopy 2012;29(7):380-384
CountryChina
Language:Chinese
Abstract: Objective To investigate the safety and efficiency of 125I radioactive stents for advanced extra-hepatic cholangio-carcinoma.Methods We retrospectively reviewed data of 15 consecutive patients with advanced and un-resectable extra-hepatic cholangiocarcinoma,who were treated by radioactive stents.Postoperative complications,patency time of stents,and survival of the patients were assessed.Results Fifteen patients underwent 32 endoscopic sessions of radioactive stents placement.Successful operations were achieved in all patients,and there were no life-threatening complications including perforation,bleeding or bone marrow depression.The average patency time of radioactive stents was 117 ± 105 days (8-295 days).The actual radiation dose was 56.55 ± 17.42 Gy (7.86-82.48 Gy).The median survival time was 420 days (90-1175 days) and survival of 6 patients exceeded 12 months.Conclusion The 125I radioactive stent is safe and effective for patients with advanced unresectable extra-hepatic cholangio-carcinoma.