The differences and similarities between polypoidal choroidal vasculopathy and age related macular degeneration is worthy for further investigation

VernacularTitle:值得进一步深入研究的眼底病热点:息肉样脉络膜血管病变与老年性黄斑变性的异同
Author: Xiaoxin LI
Publication Type:Journal Article
Keywords: Choroid diseases/epidemiology; Choroid diseases/etiology; Choroid diseases/pathology; Choroid diseases/diagnosis; Editorial
From: Chinese Journal of Ocular Fundus Diseases 2012;28(5):433-435
CountryChina
Language:Chinese
Abstract: Polypoidal choroidal vasculopathy (PCV) is one of the exudative maculopathy,which is characterized by retinal pigment epithelium detachment,subretinal hemorrhages and sensory retinal detachment.The prevalence of polypoidal choroidal vasculopathy (PCV) reached 33.5％ in neovascular age related macular degeneration (AMD) for Chinese population.Indocyanine green angiography showed a single or multiple focal nodular areas of hyperfluorescence arising from the choroidal circulation and currently is recognized a gold standard for diagnosis of PCV.The histopathologic findings indicated that hyalinization of choroidal vessels,like arteriosclerosis.Up to now there is no reliable evidence to demonstrate the difference in genetic study.The study of environment factor showed hypertension is associated with PCV closely than with AMD.PCV and AMD is different genotype or different phenotype as well as difference in pathogenesis need further studies.