Intraductal radiofrequency ablation for malignant biliary strictures
10.3760/cma.j.issn.1007-5232.2012.09.003
- VernacularTitle:腔内射频消融治疗胆管恶性狭窄的初步研究
- Author:
Bing HU
;
Jun WU
;
Daojian GAO
;
Yamin PAN
;
Zhimei SHI
;
Hui HUANG
;
Shuping WANG
;
Rui LU
- Publication Type:Journal Article
- Keywords:
Cholangiopancreatography,endoscopic retrograde;
Biliary tract neoplasms;
Radiofrequency ablation
- From:
Chinese Journal of Digestive Endoscopy
2012;29(9):487-490
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the feasibility and safety of endoscopic intraductal radiofrequency ablation (RFA) for unresectable malignant biliary strictures.MethodsA total of 12 patients with malignant biliary obstructions,who were unsuitable for surgical resection,were prospectively selected for this study.During ERCP,when successful biliary cannulation achieved,a bipolar radiofrequency probe was introduced into bile duct over a guidewire.RFA was given to the tumor lesion under fluoroscopy,followed by stent placement.The patients were closely observed and followed up after the procedure.ResultsSuccessful RFA was achieved in all patients before stents insertion ( plastic and metal stents in 6 respectively,additional pancreatic stents were given to 3).Mild complications of cholangitis and pancreatitis occurred in 1 patient respectively,which were cured with short-term management.Jaundice was promptly controlled in 7 patients (58.3％ ).During the mean follow-up duration of 3.4 (range 0.5-5.5) months,one patient died of cardiocerebral accident and others survived without obvious disconffort.The 1- month and 3- month stent patency was 100％ (12/12) and 80％ (8/10),respectively.ConclusionIt is technically feasible and safe to perform endoscopic intraductal RFA for the palliation of biliary malignancies.The short-term outcome is satisfying,however,long-term result and the better therapeutic schedule need further evaluation.
