Photodynamic Therapy for Bowen's Disease of the Vulva Area.
- Author:
Hong Kyu KANG
1
;
Jeong Hwan YUN
;
Young Min SON
;
Joo Young ROH
;
Jong Rok LEE
Author Information
- Publication Type:Case Report
- Keywords: Bowen's disease; Photochemotherapy; Vulva area
- MeSH: Adult; Bites and Stings; Bowen's Disease*; Carcinoma, Squamous Cell; Female; Humans; Photochemotherapy*; Recurrence; Sensation; Vulva*
- From:Annals of Dermatology 2014;26(2):241-245
- CountryRepublic of Korea
- Language:English
- Abstract: Bowen's disease is a squamous cell carcinoma in situ and has the potential to progress to a squamous cell carcinoma. The authors treated two female patients (a 39-year-old and a 41-year-old) with Bowen's disease in the vulva area using topical photodynamic therapy (PDT), involving the use of 5-aminolaevulinic acid and a light-emitting diode device. The light was administered at an intensity of 80 mW/cm2 for a dose of 120 J/cm2 biweekly for 6 cycles. The 39-year-old patient showed excellent clinical improvement, but the other patient achieved only a partial response. Even though one patient underwent a total excision 1 year later due to recurrence, both patients were satisfied with the cosmetic outcomes of this therapy and the partial improvement over time. The common side effect of PDT was a stinging sensation. PDT provides a relatively effective and useful alternative treatment for Bowen's disease in the vulva area.
