Electrophysiological characteristics in patients with early Guillain-Barré syndrome
10.3760/cma.j.issn.1006-7876.2011.11.003
- VernacularTitle:早期吉兰-巴雷综合征的神经电生理特点分析
- Author:
Tao PAN
;
Zhirong JIA
;
Tingting WANG
;
Hongxia WANG
;
Xin SHI
;
Wei LIANG
- Publication Type:Journal Article
- Keywords:
Guillain-Barré syndrome;
Electrophysiology;
H-reflex;
Neural conduction
- From:
Chinese Journal of Neurology
2011;44(11):735-738
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics of the F waves,H-reflex and nerve conductions and its diagnostic value in the patients with Guillain-Barré syndrome(GBS)onset within 4 weeks.Methods The electrophysiological data of the 40 patients with GBS were analyzed retrospectively.These patients were divided into 2 groups according to the duration of illness including in 2 week' s group and over 2 week' s group.The results of the F waves,H-reflex,the motor nerve conduction velocity (MCV),and the sensory nerve conduction velocity(SCV)of these patients were analyzed.Results The abnormality rate of the F waves was 17/20 and 7/18 respectively in less 2 week' s group and over 2 week' s.The H-reflexes were 13/20 and 12/19.The MCV was 28.4％(25/88)and 32.9％(26/79).The distal motor latency was 40.9％(36/88)and 36.7％(29/79).The compound muscle action potential amplitude was 35.2％(31/88)and 32.9％(26/79)respectively in these two groups.The abnormality rate of the SCV was 11.2％(10/89)and 25.2％(24/95)respectively in the two groups.The higher abnormality rate of these tests was the F waves and H-reflex in both the groups.The abnormality rates of the F waves(x2 =8.657,P =0.003)and SCV(x2 =6.002,P =0.014)were significantly different between the two groups.There were no significant differences in the other tests.Conclusion The electrophysiological tests are valuable in the diagnosis of GBS.The F waves and H-reflex are more significant for early diagnosis of GBS.
