Contrast-enhanced harmonic EUS in diagnosis of pancreatic occupying lesions
10.3760/cma.j.issn.1007-5232.2011.11.009
- VernacularTitle:谐波造影增强超声内镜技术在胰腺占位性疾病中的诊断作用研究
- Author:
Minmin ZHANG
;
Zhaoshen LI
;
Zhendong JIN
;
Dong WANG
;
Xianbao ZHAN
;
Can XU
;
Luowei WANG
;
Aiqiao FANG
;
Chunhua ZHANG
- Publication Type:Journal Article
- Keywords:
Pancreatic diseases;
Endoscopic ultrasonography;
Diagnosis;
Contrast enhanced harmonic
- From:
Chinese Journal of Digestive Endoscopy
2011;28(11):627-631
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the accuracy of contrast-enhanced harmonic EUS (CEH-EUS) by using a second-generation contrast medium in differential diagnosis of pancreatic occupying lesions.MethodsPatients with suspected pancreatic neoplasms or chronic pancreatitis were enrolled and underwent CEH-EUS by using ultrasonic contrast medium Sonovue.Cytological and/or histological diagnoses were made by EUS-FNA and the final follow-up results.Characteristics of enhancement of the target areas,such as enhancement sequence,time features,pattern grade and venous elution degree were investigated.ResultsA total of 23 patients were enrolled,in which 13 were diagnosed with FNA as having pancreatic cancer,7 with chronic pancreatitis,2 with intraductal papillary mucinous neoplasms and 1 with microcystic serous cystadenoma.The accuracy of CEH-EUS was 95.65％,which was significantly higher than that of conventional EUS (78.2％).Enhancement of pancreatic cancer by CEH-EUS was later than or simultaneous with the nearby tissues,with heterogeneous low enhancement or fulfillment defect areas,and early subsidence without obvious peak.Enhancement of benign pancreatic diseases was simultaneous with the surrounding tissues,with homogenous fulfillment and simultaneous subsidence.ConclusionCEH-EUS is safe,convenient and accurate in diagnosis of pancreatic occupying lesions and can be used as an additional diagnostic method to EUSFNA.
