Molecular epidemiology of noroviruses from infantile diarrhea at Suzhou and Nanjing area in Jiangsu province in 2010
10.3760/cma.j.issn.0254-5101.2011.11.009
- VernacularTitle:江苏省苏州及南京地区2010年婴幼儿腹泻中诺如病毒分子流行病学研究
- Author:
Jianguang FU
;
Bin WU
;
Hong JI
;
Liang LI
;
Xian QI
;
Yuanfang QIN
;
Shenjiao WANG
;
Fei DENG
;
Zhifeng LI
;
Fenyang TANG
;
Rongqiang ZU
;
Changjun BAO
- Publication Type:Journal Article
- Keywords:
Norovirus;
Genotype;
Phylogenetic tree
- From:
Chinese Journal of Microbiology and Immunology
2011;31(11):989-993
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate norovirus infection status and indentify its epidemiological characteristics and genotype distribution in infantile viral diarrhea in Jiangsu.MethodsFour hundred and ninety-eight fecal specimens of infantile virus diarrhea cases were collected from Suzhou Children's hospital and Nanjing Children's hospital in 2010.Norovirus genegroup were detected by real-time RT-PCR,and genetype were determined by sequence analysis.Results Among all fecal specimens,2 (0.4%) cases were positive for norovirus G Ⅰ,and 190 (38%) cases for G Ⅱ.Nucleotide sequence analysis revealed that in the 2 samples for G Ⅰ,one strain was G Ⅰ 1 and another was G Ⅰ 3.Twenty-one strains were belonged to G Ⅱ 4 and 2 strains were G Ⅱ 3 in the 23 samples for G Ⅱ.ConclusionAs one of the most important pathogens causing infantile viral diarrhea in Jiangsu province,subtype G Ⅱ 4 was the main epidemic strain of norovirus,meanwhile other genotypes also existed.