Clinicopathology of 202 diabetes mellitus patients complicated with non-diabetic renal diseases
10.3760/cma.j.issn.1001-7097.2011.10.002
- VernacularTitle:202例糖尿病患者并发非糖尿病性肾损害的临床病理
- Author:
Wenwen REN
;
Wenge LI
;
Guming ZOU
;
Jing FANG
;
Jianhua LU
;
Yali CAO
;
Li ZHUO
;
Wanzhong ZOU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Kidney diseases;
Pathology,clinical;
Age
- From:
Chinese Journal of Nephrology
2011;27(10):720-723
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the clinicopathological characteristics of non-diabetic renal diseases (NDRD) in the patients with diabetes mellitus.MethodsClinicopatholigical data of 202 patients with diabetes mellitus and NDRD identified by renal biopsy from January 1st,2003 to December 31st,2010 were analyzed retrospectively.All the patients were divided into three groups:the young (≤35 years old),the middle-aged (36-59 years old) and the elder (≥60 years old).Clinicopathological characteristics were compared among 3 groups.ResultsIn the young group (n=33),42.4％ of patients presented as chronic glomerulonephritic syndrome,while 36.4％ as IgA nephropathy for pathology.In the middle-aged group(n=136),35.3％ of patients presented as chronic glomerulonephritic syndrome,27.2％ as nephritic syndrome,17.6％ as chronic renal failure,14.7％ as latent glomerulonephritis,and 5.1％ as acute renal failure,while42.6％ as IgA nephropathy for pathology.In the elder group(n=33),30.3％ of patients presented as nephritic syndrome,30.3％ as chronic renal failure,while 27.3％ as membranous nephropathy for pathology.ConclusionsIn clinical manifestation,young patients are mainly chronic glomerulonephritic syndrome,middle-aged patients are diversified,and elder patients are mainly nephritic syndrome andchronicrenalfailure. Inpathology, youngandmiddle-agedpatientsaremainlyIgA nephropathy,and elder patients are mainly membranous nephropathy.
