Hybrid trans-gastric endoscopic and laparoscopic cholecystectomy in a porcine model
10.3760/cma.j.issn.1007-5232.2011.05.009
- VernacularTitle:经胃途径内镜联合腹腔镜胆囊切除术的动物实验研究
- Author:
Zhanguo CAO
;
Mingfang QIN
;
Qing WANG
;
Fusheng ZOU
;
Ping YUE
- Publication Type:Journal Article
- Keywords:
Laparoscopic cholecystectomy;
Gastrointestinal endoscopes;
Laboratory animals
- From:
Chinese Journal of Digestive Endoscopy
2011;28(5):263-265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the safety and feasibility of hybrid trans-gastric endoscopic and laparoscopic cholecystectomy in a porcine model.Methods A total of 6 pigs underwent hybrid trans-gastric endoscopic and laparoscopic cholecystectomy from July to October,2010 under general anesthesia.The operation time and complications during the procedure were recorded,as well as post-operative changes of eating habits and weight.Animals underwent autopsies on post-operative days(POD)14 for evaluation of infection,abscesses and adhesion.Results All procedures were successfully performed and all dogs survived.There was no severe complication except for hemorrhage in one porcine,which was successfully managed under laparoscopy.The mean operation time was 87mins(ranging from 69-124 mins).After the operation,there was no change in eating habits or weight.At autopsy on POD 14,no abscess or hemorrhage was found.Sites of gastric closure were found to be completely healed.Conclusion The hybrid approach increases the safety of initial gastric puncture and gastric wall incision,simplifies peroral trans-gastric cholecystectomy,and decreases invasiveness of laparoscopic surgery.It is a bridge between laparoscopic and transluminal surgery.
