Diagnosis, treatment and prognosis of rectal cancer after renal transplantation
10.3760/cma.j.issn.1006-9801.2011.11.010
- VernacularTitle:肾移植后直肠癌的诊治及预后分析
- Author:
Haiyi LIU
;
Xiaobo LIANG
;
Ning LI
;
Yaoping LI
;
Yi FENG
;
Lichun WANG
;
Shenghuai HOU
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Kidney transplantation;
Therapy;
Prognosis
- From:
Cancer Research and Clinic
2011;23(11):756-758
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis,the treatment methods and the prognosis of rectal cancer patients after renal transplantation.Methods Four patients with rectal cancer were found in 1035 renal transplantation recipients.Three of four patients were treated with anterior resection (AR) or abdomenoperineal resection (APR) with total mesorectal excision (TME).The two patients accepted regular adjuvant chemotherapy for six months period after surgery,but one patient rejected to accept any chemotherapy after surgery.Otherwise,one patient was only treated with chemotherapy and best support therapy for diagnosed as rectal cancer with multiple liver metastases.Results Two patients were fine to be followed up,8 months and 21 months after rectal resection respectively.Two other patients eventually died of metastasized cancer 5 months and 31 months respectively after therapy had been initiated.Conclusion Transplantation patients should receive standard oncology treatment,including operation and adjuvant treatment,so long as their general condition and organ graft functions allow to do so,although a higher degree of morbidity might be encountered,and periodical colorectal screening should be performed before and after renal transplantation.
