The clinical analysis of the synchronous multiple primary esophageal carcinoma
10.3760/cma.j.issn.1001-4497.2011.010.009
- VernacularTitle:同时性多原发食管癌
- Author:
Tao YU
;
Jianye LI
;
Jian JIANG
;
Yunfei ZHANG
;
Fei LI
;
Zhen YU
;
Nan KE
- Publication Type:Journal Article
- Keywords:
Esophageal carcinoma;
Neoplasms,multiple primary;
Thoracic surgical procedures
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2011;27(10):604-606
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics,the diagnosis and therapy of synchronous multiple primary esophageal carcinoma.Methods Thirty-two cases of synchronous multiple primary esophageal carcinoma were collected from January 1980 to December 2010 and their clinic data were retrospectively analysised.Results In the whole group,there were totally 66 lesions in 30 cases of double primary lesion and 2 cases of three primary lesion.The length of the lesions were 1 cm to 6.5 cm,and there were 22 lesions in cervical esophagus,10 in upper thoracic esophagus,19 in midthoracic esophagus and 15 in lower thoracic esophagus.Within the 66 lesions,65 lesions were squamous cell carcinoma and 1 was adenocarcinoma.The mucosa between the lesions were normal,with a distance of 4 cm to 9.5 cm,average 7.1 cm.Thirty-two patients with synchronous multiple primary esophageal carcinoma received surgery.Among 32 cases,26 of them were given definite diagnosis before operation.Four of them had exploratory operation,one patient underwent palliative resection,27 patients underwent radical resection.Two cases of the pathologic results of esophageal stump showed carcinoma after operation.The complications occurred in 8 patients.Twenty-eight cases were followed up after operation,the 1,3 and 5-survival rate were 76.9％,43.3 and 14.8％,respectively.Conclusion General pre-operation examination can significant helpful for the definite diagnosis of synchronous multiple primary esophageal carcinoma and surgical treatment is better choice for this disease.
