Palisaded Encapsulated Neuroma with Unusual Clinical Features: 1 Case.
- Author:
Soo Ick CHO
1
;
Jin Hye KIM
;
Bo Young CHUNG
;
Jeong Won KIM
;
Hye One KIM
;
Chun Wook PARK
;
Cheol Heon LEE
Author Information
1. Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea. dermlee@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Back;
Pain;
Palisaded encapsulated neuroma
- MeSH:
Adult;
Dermis;
Female;
Humans;
Mucin-1;
Neuroma;
S100 Proteins;
Sensation;
Young Adult
- From:Korean Journal of Dermatology
2012;50(8):734-737
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Palisaded encapsulated neuroma (PEN) is a rare, benign, cutaneous nerve sheath tumor, which usually appears as a solitary asymptomatic skin-colored papule, which usually affects the face of middle-aged adults. Here, we report a case of PEN with unusual clinical features in a 23-year-old female, developed on the back, accompanied with pain sensation. Histopathologically, it appeared as a well-circumscribed, encapsulated round nodule, consisted of uniform, broad, and interlacing fascicles of the spindle cells in the dermis. On immunohistochemical staining, the tumor cells of nodule were positive for S-100 protein and neural filaments, while the capsule of the nodule was focally positive for the epithelial membrane antigen.
