A Case of Dermatomyositis with Acute Interstitial Pneumonitis Manifested as Antisynthetase Syndrome.
- Author:
Hyun Ho SON
1
;
Se Won JUNG
;
Hyun Soo SIM
;
Sook Kyung LEE
Author Information
1. Department of Dermatology, Maryknoll Medical Center, Busan, Korea. sea7th@naver.com
- Publication Type:Case Report
- Keywords:
Antisynthetase syndrome;
Dermatomyositis;
Interstitial lung disease
- MeSH:
Antibodies, Antinuclear;
Dermatomyositis;
Female;
Humans;
Lung;
Lung Diseases, Interstitial;
Muscle, Skeletal;
Myositis;
Prognosis;
Respiratory Distress Syndrome, Adult;
Skin
- From:Korean Journal of Dermatology
2012;50(8):742-746
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dermatomyositis is a systemic inflammatory disease affecting the skin, skeletal muscle, and occasionally, other organs, such as the lung. Interstitial lung disease (ILD) is a serious lung complication, which can occur in patients with dermatomyositis. It affects the prognosis of the disease and requires a more aggressive therapeutic approach. Interstitial lung disease (ILD) may be associated with systemic inflammatory disorders and autoantibody production. In particular, anti Jo-1 antibody has long been recognized as an important predictive factor in systemic manifestations of ILD in dermatomyositis. We report here a case of a 42 year old woman with cutaneous lesions typical of dermatomyositis, showing clinical features of antisynthetase syndrome, which showed rapid progression to acute respiratory distress syndrome.
