Subjective global assessment predicts the prognosis of patients with hospital-acquired acute kidney injury
10.3760/cma.j.issn.1001-7097.2011.08.004
- VernacularTitle:主观综合性营养评估预测急性肾损伤患者的预后
- Author:
Ying ZHOU
;
Huifang GU
;
Qionghong XIE
;
Zhongye XU
;
Shuai MA
;
Huaizhou YOU
;
Dingwei KUANG
;
Yong GU
;
Chuanming HAO
;
Shantan LIN
;
Feng DING
- Publication Type:Journal Article
- Keywords:
Nutrition assessment;
Kidney insufficiency,acute;
Mortality;
Subjective Global Assessment
- From:
Chinese Journal of Nephrology
2011;27(8):567-571
- CountryChina
- Language:Chinese
-
Abstract:
Objective To elucidate the malnutrition in patients with hospital-acquired acute kidney injury(AKI), and to examine the association betweensubjective global assessment (SGA) and prognosis.Methods Adult patients with hospital-acquired AKI were prospectively enrolled in this cohort study.Nutritional evaluations, including SGA, anthropometric and serum nutritional markers were conducted at enrollment.Overall survival at 90 days among different SGA scores was analyzed using Kaplan-Meier methods, and differences were tested using the log-rank test.The Cox model was used to analyze the relationship between SGA scores and all-cause mortality after adjusting for confounders.Results A total of 170 patients were enrolled.The prevalence of moderate malnutrition(SGA B) and severe malnutrition(SGA C) was 51.8% and 22.9% respectively, while patients with normal nutrition(SGA A) accounted for 25.3%.After 90 days follow-up, all-cause mortality was 9.8% in SGA A group, 34.9% in SGA B group and 56.8%inSGACgrouprespectively. Afteradjustingforage,sex,dialysis,ventilation, hemoglobin, platelets and bilirubin, the hazard ratio(HR) of 90 days all-cause mortality was 4.0(95% CI 1.42-11.22, P=0.008) in malnutrition group (SGA B group and SGA C group) compared with SGA A group.The Kaplan-Meier curve also revealed that the worse the SGA score was, the lower the cumulative survival became (P<0.01).Conclusion SGA score is an independent risk factor for all-cause mortality within 90 days in patients with hospital-acquired acute kidney injury.