The safety of endoscopic ligation of gastric and colic full-thickness wall with detachable nylon loops

VernacularTitle:尼龙圈结扎胃结肠壁全层安全性的初步实验研究
Author: Jitao SONG ; Jibin YIN ; Bingrong LIU ; Jimei YIN ; Dan LIU ; Yawen YANG ; Hui LI
Publication Type:Journal Article
Keywords: Ligation; Animals experimentation; Nylons; Safety
From: Chinese Journal of Digestive Endoscopy 2011;28(7):383-385
CountryChina
Language:Chinese
Abstract: Objective To evaluate the safety of endoscopic ligation of gastric and colic full-thickness wall with nylon loops.Methods Endoscopic ligation of full gastric and colic wall with detachable nylon loops, assisted by laparotomy, were performed in 4 dogs.Ligation healing was assessed on 3, 7, 10and 17 days after the procedure.Results All animals recovered after the procedure, without any clinical signs of infection or hemorrhage.Postoperative examination did not reveal gastric or colonic perforation, or local abscess.Loop ligature showed ulcer-like lesion.Histopathology revealed muscularis propria disruption, granulation tissue bridging the site of ligation and formation of scar tissue.Regenerative mucosa coyered the surface of the ligature completely 17 days after the operation.Conclusion Endoscopic ligation of gastric and colic full-thickness wall with detachable nylon loops is safe.Its application can be extended to other fields.